PRUNE, the human homologue of the Drosophila gene, is located in 1q21.3, a region highly amplified in human sarcomas, malignant tumours of mesenchymal...
The deduced 2,714-amino acid protein has a coiled-coil sequence, a proline-rich region, a P loop, and a C-terminal BNIP2 and CDC42GAP (ARHGAP1) homology...
Periaxin is a protein involved in peripheral nerve myelin upkeep. The encoded protein contains 2 PDZ domains which were named after PSD95 (post synaptic...
Persephin is a neurotrophic factor, belonging to the GDNF family. Neurotrophic factors are important for the proper development and maintenance of the...
PTEN acts as a tumor suppressor gene through the action of its phosphatase protein product. This phosphatase is involved in the regulation of the cell cycle,...
Prostaglandin D synthase catalyzes the conversion of prostaglandin H2 (PGH2) to postaglandin D2 (PGD2). Prostaglandin D synthase induces sleep, regulates...
Prostacyclin receptor is a member of the G-protein coupled receptor family. Prostacyclin, the major product of cyclooxygenase in macrovascular endothelium,...
Prostaglandin I2 (prostacyclin) synthase is a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which...
PTGR1 isan enzyme that is involved in the inactivation of the chemotactic factor, leukotriene B4. The encoded protein specifically catalyzes the NADP+...
There are two isozymes of PTGS: a constitutive PTGS1 and an inducible PTGS2, which differ in their regulation of expression and tissue distribution. PTGS1,...
Parathyroid hormone-related protein (or PTHrP) is a protein occasionally secreted by cancer cells (breast cancer, certain types of lung cancer including...
Parathymosin is a polypeptide similar in size and amino acid composition to prothymosin-alpha. It has a high content of dicarboxylic amino acids and a...
PTOV1 was predicted to form alternating alpha helices and beta sheets. Normal prostate expressed low PTOV1 levels. Western blot analysis of prostate tumor...
Protein tyrosine phosphatase type IVA 1 is an enzyme belongs to a small class of prenylated protein tyrosine phosphatases (PTPs), which contains a PTP domain...
Protein tyrosine phosphatase type IVA 2 is an enzyme belongs to a small class of the protein tyrosine phosphatase (PTP) family. PTPs are cell signaling...
Protein tyrosine phosphatase type IVA 3 is an enzyme belongs to a small class of prenylated protein tyrosine phosphatases (PTPs). PTPs are cell signaling...
Tyrosine-protein phosphatase non-receptor type 4 is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that...
Protein tyrosine-protein phosphatase required for T-cell activation through the antigen receptor. Acts as a positive regulator of T-cell coactivation upon...
T is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes...
Receptor-type tyrosine-protein phosphatase U is a member of the protein tyrosine phosphatase (PTP) family. This PTP possesses an extracellular region, a...