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Mouse Prostacyclin receptor (PTGIR) ELISA Kit

Cat no: KTE70624

Mouse Prostacyclin receptor (PTGIR) ELISA Kit

Prostacyclin receptor is a member of the G-protein coupled receptor family. Prostacyclin, the major product of cyclooxygenase in macrovascular endothelium, elicits a potent vasodilation and inhibition of platelet aggregation through binding to this receptor.\nWhen binding a prostacyclin-molecule, the receptor changes conformation and activates Gs, with its activation of cAMP and increase in protein kinase A (PKA) activity.In vasodilation, the PKA activity causes phosphorylation of MLCK, decreasing its activity, resulting in dephosphorylation of MLC of myosin. The smooth muscle relaxation leads to vasodilation.

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SPECIFICATIONS

Catalog Number

KTE70624

Size

48T, 96T, 96T*5, 96T*50

Applications

ELISA

Reactivities

Mouse

Gene Id

19222

Accession

P43252

Additional Info

Mouse Prostacyclin receptor (PTGIR) ELISA Kit has high sensitivity and excellent specificity for detection of Mouse PTGIR. No significant cross-reactivity or interference between Mouse PTGIR and analogues was observed.

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