Mouse Prostaglandin G/H synthase 1 (PTGS1) ELISA Kit

There are two isozymes of PTGS: a constitutive PTGS1 and an inducible PTGS2, which differ in their regulation of expression and tissue distribution. PTGS1, which regulates angiogenesis in endothelial cells, and is inhibited by nonsteroidal anti-inflammatory drugs such as aspirin. Recent research has shown that the inhibition of COX-1 is the main reason why aspirin is effective at reducing cardiac events (as opposed to aspirin's anti-platelet aggregation effects).\nPTGS1 is thought to be involved in cell-cell signaling and maintaining tissue homeostasis. Alternative splicing of this gene generates two transcript variants called COX-1 and COX-3. The expression of these two transcripts is differentially regulated by relevant cytokines and growth factors.

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SPECIFICATIONS

Catalog Number

KTE70621

Size

48T, 96T, 96T*5, 96T*50

Applications

ELISA

Reactivities

Mouse

Gene Id

19224

Accession

P22437

Additional Info

Mouse Prostaglandin G/H synthase 1 (PTGS1) ELISA Kit has high sensitivity and excellent specificity for detection of Mouse PTGS1. No significant cross-reactivity or interference between Mouse PTGS1 and analogues was observed.