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Phosphatidylinositol 3-kinase (PI3K) is a lipid kinase that phosphorylates the inositol ring of phosphatidylinositol and related compounds at the 3-prime...
PIM2 encodes a protooncogene that acts as a serine/threonine protein kinase. Studies determined the encoded protein functions to prevent apoptosis and to...
The deduced 326-amino acid protein has a calculated molecular mass of 35.9 kD. PIM3 shares 95% amino acid identity with rodent Pim3 and 57.1% and 44.0% amino...
Peptidyl-prolyl cis/trans isomerases (PPIases; EC 5.2.1.8), such as PIN1, catalyze the cis/trans isomerization of peptidyl-prolyl peptide bonds. PIN1 is the...
PITX1 encodes a member of the RIEG/PITX homeobox family, which is in the bicoid class of homeodomain proteins. According to an October 2008 press release by...
PITX2 encodes a member of the RIEG/PITX homeobox family, which is in the bicoid class of homeodomain proteins. This protein acts as a transcription factor...
Polycystin-1 is a protein that in humans is encoded by the PKD1 gene.Splice variants encoding different isoforms have been noted for PKD1. The gene is...
The predicted 195-amino acid human protein shares 90% identity with the mouse protein and 40% identity with human PLA2G12A. It contains a 19-amino acid...
Phospholipases A2 (PLA2s) hydrolyze the sn-2 fatty acid acyl ester bond of phosphoglycerides, releasing free fatty acids and lysophospholipids. PLA2G2A...
PLA2G2D, The extracellular forms of phospholipases A2 have been isolated from different venoms (snake, bee, and wasp), from virtually every studied mammalian...
PLA2G4D acts as a calcium-dependent phospholipase A2 enzyme with a lineolic acid-specific activity. Using in situ hybridization and immunohistochemistry of...
PLA2G5 is located in a tightly-linked cluster of secretory phospholipase A2 genes on chromosome 1. The encoded enzyme catalyzes the hydrolysis of membrane...
85 kDa calcium-independent phospholipase A2 is is an A2 phospholipase, a class of enzyme that catalyzes the release of fatty acids from phospholipids. The...
Lipoprotein-associated phospholipase A2 (Lp-PLA2, also known as platelet activating factor acetyl-hydrolase), is a relatively recent marker that has emerged...
Phospholipase A2-activating protein (PLAP) is potentially important in regulating the inflammatory response through its activation of phospholipase A2, which...
PLAC8 (Placenta Specific 8) is a Protein Coding gene. Among its related pathways are Immune System and Glucose / Energy Metabolism. GO annotations related to...
Plat encodes a key enzyme of the fibrinolytic pathway. The plasminogen activator, tissue undergoes proteolytic processing by plasmin to generate a...
Urokinase-type plasminogen activator is a serine protease involved in degradation of the extracellular matrix and possibly tumor cell migration and...
uPAR consists of three different domains of the Ly-6/uPAR/alpha-neurotoxin family. All three domains are necessary for high affinity binding of the primary...
Overexpressed wildtype rat Plcg1 or a lipase-inactive mutant Plcg1 each augmented ACE in rat PC12 cells, while a deletion mutant lacking the region...
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