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Human Cytochrome b-245 heavy chain (CYBB) ELISA Kit

Cat no: KTE62182

Human Cytochrome b-245 heavy chain (CYBB) ELISA Kit

Cytochrome b (-245) is composed of cytochrome b alpha (CYBA) and beta (CYBB) chain. It has been proposed as a primary component of the microbicidal oxidase system of phagocytes. CYBB deficiency is one of five described biochemical defects associated with chronic granulomatous disease (CGD). In this disorder, there is decreased activity of phagocyte NADPH oxidase; neutrophils are able to phagocytize bacteria but cannot kill them in the phagocytic vacuoles. The cause of the killing defect is an inability to increase the cell's respiration and consequent failure to deliver activated oxygen into the phagocytic vacuole.

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SPECIFICATIONS

Catalog Number

KTE62182

Size

48T, 96T, 96T*5, 96T*50

Applications

ELISA

Reactivities

Hum

Gene Id

1536

Accession

P04839

Additional Info

Human Cytochrome b-245 heavy chain (CYBB) ELISA Kit has high sensitivity and excellent specificity for detection of Human CYBB. No significant cross-reactivity or interference between Human CYBB and analogues was observed.

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SUPPLIER INFO

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