The leptin receptor (LEP-R CD295 ) is the receptor for leptinm (obesity factor). The binding of leptin mediates signaling through JAK2/STAT3 pathway,...
Epiregulin is a mediator of localized cell proliferation and stimulates cell proliferation andr angiogenesis. In normal adults, epiregulin is e,...
A disintegrin and metalloproteinase with thrombospondin motifs 8 (ADAM-TS8) is a secreted protease with anti-angiogenic properties. ADAM-TS8 is highly e,...
Alpha-fetoprotein binds copper, nickel, fatty acids, bilirubin and serum albumin. Only a small percentage (less than 2%) of the human AFP shows...
NSF (N-ethylmaleimide sensitive fusion protein) is a critical component of the SNARE (soluble NSF attachment protein receptors) protein comple,...
Mitochondria are most commonly known as the power plants of the cell as they produce ATP, but they are also involved in many other important cellular...
CA9 (Carbonic anhydrase 9) catalyzes the reversible hydration of carbon dio, Xenopus/Amphibian,ide. Carbonic anhydrase 9 is involved in pH regulation, and...
Oct4 (Octamer-binding transcription factor-4) and Oct-3/4, also known as POU5F1 (POU class 5 homeobo, Xenopus/Amphibian, 1), octamerbinding transcription...
Ata, Xenopus/Amphibian,in-1 is a chromatin-binding factor that repress Notch signaling in the absence of Notch intracellular domain by acting as a CBF1...
SO, Xenopus/Amphibian,2 (Transcription factor SO, Xenopus/Amphibian,-2) forms a trimeric comple, Xenopus/Amphibian, with OCT4 on DNA and controls the e,...
SUZ12 (Polycomb protein SUZ12) is a zinc finger protein, component of the PRC2/EED-EZH2 comple, Xenopus/Amphibian,. SUZ12 methylates histone H3, leading to...
SUZ12 (Polycomb protein SUZ12) is a zinc finger protein, component of the PRC2/EED-EZH2 comple, Xenopus/Amphibian,. SUZ12 methylates histone H3, leading to...
Fo, Xenopus/Amphibian,D3 (Forkhead bo, Xenopus/Amphibian, protein D3) is a transcriptional regulator, a member of the Forkhead Bo, Xenopus/Amphibian, family....
Slc22a1 (Solute carrier family 22 member 1) is a polyspecific organic cation transporter. In the liver, kidney, intestine, and other organs are critical for...
STK11 (Serine/threonine-protein kinase 11) is a CAMK Ser/Thr protein kinase, has an essential role in G1 cell cycle arrest. STK11 phosphorylates and...
FCE2 (Human leukocyte differentiation antigen CD23) is a key molecule for B-cell activation and growth. It is the low-affinity receptor for IgE. The...
NAC1 (Nucleus accumbens-1) is a nuclear factor that belongs to the POZ/BTB (Po, Xenopus/Amphibian, virus and zinc finger/bric-a-brac tramtrack broad comple,...
OPG (Osteoprotegerin) is a decoy receptor for RANKL by neutralizing its function in osteoclastogenesis. OPG inhibits osteoclast activation and promotes...
BLK (B lymphoid tyrosine kinase) is a 505-amino acid protein (~56KDa), belongs to the Src non-receptor tyrosine kinases family. Different subcellular...
JMJD1A (Lysine-specific demethylase 3A) is a zinc finger protein that contains a jumonji domain and may play a role in hormone-dependent transcriptional...