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BLK (1E6) Antibody
ABBIOTEC

Supplier:

ABBIOTEC

Cat no: 253094

BLK (1E6) Antibody

BLK (B lymphoid tyrosine kinase) is a 505-amino acid protein (~56KDa), belongs to the Src non-receptor tyrosine kinases family. Different subcellular localizations of Src-family kinases may be important for the regulation of specific cellular processes such as mitogenesis, cytoskeletal organization and membrane trafficking. Blk is e, Xenopus/Amphibian,pressed e, Xenopus/Amphibian,clusively by B lymphocytes and it is thought to function in a signal transductory pathway specific to this lineage. B lymphoid e, Xenopus/Amphibian,pression of an active Blk mutant caused proliferation of B progenitor cells and enhanced responsiveness of these cells to interleukin 7. Thus, sustained activation of Blk induces responses normally associated with the pre-BCR.

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SPECIFICATIONS

Catalog Number

253094

Size

0.1 ml

Applications

IF

Reactivities

Hum

Format

Each vial contains 0.1 ml ascitic fluid with 0.03% sodium azide.

P Type

Mouse Monoclonal Antibody

Antigen

Purified recombinant fragment of human BLK e, Xenopus/Amphibian,pressed in E. coli.

Isotype

Mouse IgG1

Accession

P51451

Clonality

1E6

Additional Info

Tyrosine-protein kinase Blk; B lymphocyte kinase; p55-Blk; BLK

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