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LEPR Antibody
ABBIOTEC

Supplier:

ABBIOTEC

Cat no: 252113

LEPR Antibody

The leptin receptor (LEP-R CD295 ) is the receptor for leptinm (obesity factor). The binding of leptin mediates signaling through JAK2/STAT3 pathway, resulting in the regulation of fat metabolism and, in hematopoietic cells, lymphopoiesis. LEP-R CD295 forms a homodimer upon leptin binding, and the phosphorlyated receptor binds a number of SH2 domain-containing proteins such as STAT3,PorcineTPN11, and SOCS3.

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SPECIFICATIONS

Catalog Number

252113

Size

0.1 mg

Applications

WB

Reactivities

Hum

Format

Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.

P Type

Rabbit Polyclonal Antibody

Antigen

KLH-conjugated synthetic peptide encompassing a sequence within the human leptin receptor.

Isotype

Rabbit Ig

Accession

P48357

Additional Info

Leptin receptor; LEP-R; OB receptor; OB-R; HuB219; CD295; LEPR; DB; OBR

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