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BRAF (v-raf murine sarcoma viral oncogene homolog B1) is the main effectors recruited by GTP-bound Ras to activate the MEK-MAP kinase pathway. B-Raf contains...
ApoO (Apolipoprotein O) is a chrondroitin-sulfate chain containing member of the apolipoprotein family. It is an original glycoprotein up-regulated by...
CD37 is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are...
FGR (Gardner-Rasheed feline sarcoma viral oncogene homolog) is a member of the Src family of protein tyrosine kinases (PTKs). FGR contains N-terminal sites...
CD44 is a receptor for hyaluronic acid and can also interact with other ligands, such as osteopontin, collagens and matri, Xenopus/Amphibian,...
GABPA (GA binding protein transcription factor alpha subunit) is one of three GA-binding protein transcription factor subunits which functions as a...
MAPK10 (c-Jun N-terminal kinase 1 JNK1) responds to activation by environmental stress and pro-inflammatory cytokines by phosphorylating a number of...
Calreticulin is a multifunctional protein that acts as a major Ca2+-binding (storage) protein in the lumen of the endoplasmic reticulum. It is also found in...
AMACR (Alpha-methylacyl-CoA racemase) catalyzes the racemization of 2-methyl-branched fatty acid CoA esters. AMACR is responsible for the conversion of...
FER (Fer tyrosine kinase) is a member of the FPS/FES family of nontransmembrane receptor tyrosine kinases. FER shares a functional domain and is involved in...
FO, Xenopus/Amphibian,P3 (Forkhead bo, Xenopus/Amphibian, P3) is a transcription factor that plays a critical role in the control of immune response. Defects...
CHK1 (Serine/threonine-protein kinase CHK1) is required for checkpoint-medated cell cycle arrest and activation of DNA repair in response to the presence of...
Bcl-10 (B-cell CLL/lymphoma 10) is a protein containing a caspase recruitment domain (CARD). It plays an important role in apoptosis and activating NF-kappa....
Programmed cell death protein 6 (PDCD6) is a calcium-binding protein required for T-cell receptor-, Fas-, and glucocorticoid-induced cell death. PDCD6...
mRNA-decapping enzyme 1A (Dcp1A) is necessary for the degradation of mRNAs, both in normal mRNA turnover and in nonsense-mediated mRNA decay. Dcp1A removes...
Basic leucine zipper and W2 domain-containing protein 1 (BZW1) is a transcription factor that enhances histone H4 gene transcription but does not seem to...
Platelet-derived growth factor C (PDGF-C) is a potent mitogen and chemoattractant for cells of mesenchymal origin. The binding of PDGF-C growth factor to its...
Angiopoietin-1 (ANG-1) binds and activates the TIE2 receptor by inducing its tyrosine phosphorylation. ANG-1 is implicated in endothelial developmental...
n-Myc is a member of the MYC family of transcription factors and encodes a protein with a basic heli, Xenopus/Amphibian,-loop-heli, Xenopus/Amphibian, (bHLH)...
Transforming growth factor-beta-induced protein ig-h3 (BIGH3) binds to type I, II, and IV collagens. BIGH3 plays a role in cell-collagen interactions. In...
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