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Cat no: 252617

MSH2 (1B3) Antibody

MSH2 (DNA mismatch repair protein Msh2) is a component of the post-replicative DNA mismatch repair system (MMR). MSH2 forms two different heterodimers: MutS alpha (MSH2-MSH6 heterodimer) and MutS beta (MSH2-MSH3 heterodimer) that bind to DNA mismatches and initiate DNA repair. Defects in MSH2 are the cause of hereditary nonpolyposis colorectal cancer type 1 and endometrial cancers.

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SPECIFICATIONS

Catalog Number

252617

Size

0.1 ml

Applications

IF, IHC

Reactivities

Hum, Mouse

Format

Each vial contains 0.1 ml ascitic fluid with 0.03% sodium azide.

P Type

Mouse Monoclonal Antibody

Antigen

Purified recombinant fragment of human MSH2 e, Xenopus/Amphibian,pressed in E. coli.

Isotype

Mouse IgG1

Accession

P43246, NP_000242

Clonality

1B3=3A2B8C

Additional Info

DNA mismatch repair protein Msh2; MutS protein homolog 2; MSH2

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