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STK11, a CAMK Ser/Thr protein kinase, has an essential role in G1 cell cycle arrest. STK11 phosphorylates and activates members of the AMPK-related subfamily...
Rab proteins belong to the Ras small GTPase superfamily. The GTP-binding Rab3 subfamily has 4 known isoforms: 3A, 3Bovine, 3C, and 3D. Rab3 is e,...
E, Xenopus/Amphibian,ostosin-1 (E, Xenopus/Amphibian,T1) is a glycosyltransferase required for the biosynthesis of heparan-sulfate. The E,...
CaM Kinase 2 alpha (CAMKII alpha) is a prominent Ser/Thr kinase in the central nervous system that functions in long-term potentiation and neurotransmitter...
Cleavage stimulation factor 64 kDa subunit (CstF-64) is one of the multiple factors required for polyadenylation and 3'-end cleavage of mammalian pre-mRNAs....
2',3'-cyclic-nucleotide 3'-phosphodiesterase (CNPase A) is a phosphodiesterase that catalyzes the following reaction: Nucleoside 2',3'-cyclic phosphate + H2O...
Angiotensin-converting enzyme (ACE) is important for blood pressure homeostasis through generation of the vasoconstrictor angiotensin II and inactivation of...
Surfactant protein A (SP-A) is synthesized and secreted by lung epithelial cells. It belongs to group III of the family of C-type lectins and members of this...
PI3KC3 is the catalytic subunit of the PI3K comple, Xenopus/Amphibian, and is involved in the transport of lysosomal enzyme precursors to lysosomes. PI3KC3...
WT1 has a potential role in transcriptional regulation by recognizing and binding to the DNA sequence 5'-CGCCCCCGC-3'. Defects in WT1 are the cause of...
Tissue inhibitor of metalloproteinases 1 (TIMP-1) binds to metalloproteinases such as collagenases and irreversibly inactivates the proteases. TIMP-1 is...
T-lymphocyte activation antigen CD86 (CD86), a receptor for CD28 or CTLA-4, is involved in the co-stimulatory signal essential for T-lymphocyte proliferation...
Glucagon-like peptide-2 (GLP-2) is liberated in the intestinal L cells after glucagon processing. GLP-2 stimulates intestinal growth and up-regulates villus...
GLP-1 stimulates glucose-dependent insulin release, therefore suppressing plasma glucagon levels, and stimulating glucose disposal in peripheral tissues. In...
Paired bo, Xenopus/Amphibian, protein Pa, Xenopus/Amphibian,-2 (Pa, Xenopus/Amphibian,-2) is a transcription factor involved in kidney cell differentiation....
Fibroblast growth factor receptor 3 (FGFR3 or CD333) is a receptor for acidic and basic fibroblast growth factors,Porcinereferentially binding FGF1. FGFR3 is...
Integrin alpha-V/beta-3, also called vitronectin receptor or CD51/CD61, belongs to the integrin protein family that participates in cell adhesion and...
Ciliary neurotrophic factor (CNTF) is a survival factor for various neuronal cell types. CNTF prevents the degeneration of motor a, Xenopus/Amphibian,ons...
Tumor necrosis factor alpha (TNF-alpha) is a cytokine that binds to the TNF-R1 and TNF-R2 receptors. TNF-alpha is mainly secreted by macrophages and induces...
Insulin, secreted from the pancreas, is a hormone which triggers a decrease in blood glucose concentration. Insulin has a structure of a B chain and an A...
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