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BCL-10 (4F8) Antibody
ABBIOTEC

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ABBIOTEC

Cat no: 252596

BCL-10 (4F8) Antibody

Bcl-10 (B-cell CLL/lymphoma 10) is a protein containing a caspase recruitment domain (CARD). It plays an important \rrole in apoptosis and activating NF-kappa. Bcl-10 interacts with CARD domain containing proteins including CARD9, 10, 11 and 14, which were thought to function as upstream regulators in NF-kappaB signaling. Bcl-10 is found to form a comple, Xenopus/Amphibian, with MALT1 which encoded by another gene known to be translocated in MALT lymphoma. MALT1 and Bcl-10 are thought to synergize in the activation of NF-kappaBovine, and the deregulation of either of them may contribute tothe same pathogenetic process that leads to the malignancy. \r

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SPECIFICATIONS

Catalog Number

252596

Size

0.1 mg

Applications

FC, IF, IHC

Reactivities

Hum, Mouse

Format

Each vial contains 0.1 mg IgG in PBS pH7.4 with 0.03% sodium azide. Antibody was purified by Protein-G affinity chromatography.

P Type

Mouse Monoclonal Antibody

Antigen

Purified recombinant fragment of human BCL-10 e, Xenopus/Amphibian,pressed in E. coli.

Isotype

Mouse IgG1

Accession

O95999

Clonality

4F8E8H8,4F8E3H8

Additional Info

Bcl-10; B-cell lymphoma/leukemia 10; B-cell CLL/lymphoma 10; CED-3/ICH-1 prodomain homologous E10-like regulator; CIPER; CARD-containing molecule enhancing NF-kappa-B; Cellular homolog of vCARMEN; cCARMEN; Mammalian CARD-containing adapter molecule E10; mE10; Cellular-E10; c-E10; CARD-like apoptotic protein; hCLAP; BCL10; CIPER; CLAP

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