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BCL-2 (8E12) Antibody
ABBIOTEC

Supplier:

ABBIOTEC

Cat no: 253037

BCL-2 (8E12) Antibody

Bcl-2 blocks cell death following a variety of stimuli and confers a death-sparing effect to certain hematopoietic cell lines following growth factor withdrawal. Bcl-2 regulates cell death by controlling the mitochondrial membrane permeability. Bcl-2 functions in a feedback loop system with caspases by inhibiting caspase activity either by preventing the release of cytochrome c from the mitochondria or by binding to the apoptosis-activating factor (APAF-1).

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SPECIFICATIONS

Catalog Number

253037

Size

0.1 ml

Applications

IF, IHC

Reactivities

Hum, Mouse

Format

Each vial contains 0.1 ml ascitic fluid with 0.03% sodium azide.

P Type

Mouse Monoclonal Antibody

Antigen

Synthetic peptide corresponding to residues surrounding BCL-2, conjugated to KLH.

Isotype

Mouse IgG1

Accession

P10415

Clonality

8E12

Additional Info

Apoptosis regulator Bcl-2; BCL2

SUPPLIER INFO

ABBIOTEC

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