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BCL-2 (8E12) Antibody

BCL-2 (8E12) Antibody

Cat no: 253037

Supplier: ABBIOTEC
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Bcl-2 blocks cell death following a variety of stimuli and confers a death-sparing effect to certain hematopoietic cell lines following growth factor withdrawal. Bcl-2 regulates cell death by controlling the mitochondrial membrane permeability. Bcl-2 functions in a feedback loop system with caspases by inhibiting caspase activity either by preventing the release of cytochrome c from the mitochondria or by binding to the apoptosis-activating factor (APAF-1).
Catalogue number: 253037
Reactivities: Human, Mouse
Applications: Immunofluorescence, Immunohistochemistry
Size: 0.1 ml
Accession: P10415
Antigen: Synthetic peptide corresponding to residues surrounding BCL-2, conjugated to KLH.
Format: Each vial contains 0.1 ml ascitic fluid with 0.03% sodium azide.
P type: Mouse Monoclonal Antibody
Isotype: Mouse IgG1
Clonality: 8E12
Additional info: Apoptosis regulator Bcl-2; BCL2
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