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Polyclonal Anti-WNT9A

Polyclonal Anti-WNT9A

Cat no: PA1316

Supplier: Boster Immunoleader
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Rabbit IgG polyclonal antibody for Protein Wnt-9a (WNT9A) detection. Tested with WB, IHC-P in Human;Mouse;Rat.
Catalogue number: PA1316
Price: $200.00
Reactivities: Human, Mouse, Rat
Applications: Immunohistochemistry, Western Blot
Size: 100ug/vial
Gene: WNT9A
Swiss prot: O14904
Form: Lyophilized
Format: Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.
Storage temp: "At -20 degree C for one year. After reconstitution, at 4 degree C for one month. It can also be aliquotted and stored frozen at -20 degree C for a longer time. Avoid repeated freezing and thawing. "
Scientific background: Wingless-type MMTV integration site family, member 9A, also known as WNT9A or WNT14, is a human gene. The WNT gene family consists of structurally related genes that encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. It is expressed in gastric cancer cell lines. The protein encoded by this gene shows 75% amino acid identity to chicken Wnt14, which has been shown to play a central role in initiating synovial joint formation in the chick limb. This gene contains 4 exons and spans about 27 kb of genomic DNA, in the chromosome 1q42 region.
References: 1. Bergstein, I.; Eisenberg, L. M.; Bhalerao, J.; Jenkins, N. A.; Copeland, N. G.; Osborne, M. P.; Bowcock, A. M.; Brown, A. M. C. : Isolation of two novel WNT genes, WNT14 and WNT15, one of which (WNT15) is closely linked to WNT3 on human chromosome 17q21. Genomics 46: 450-458, 1997. 2. Saitoh, T.; Hirai, M.; Katoh, M. : Molecular cloning and characterization of WNT3A and WNT14 clustered in human chromosome 1q42 region. Biochem. Biophys. Res. Commun. 284: 1168-1175, 2001. 3. Hartmann, C.; Tabin, C. J. : Wnt-14 plays a pivotal role in inducing synovial joint formation in the developing appendicular skeleton. Cell 104: 341-351, 2001. 4. Saitoh, T.; Hirai, M.; Katoh, M. : Molecular cloning and characterization of WNT3A and WNT14 clustered in human chromosome 1q42 region. Biochem. Biophys. Res. Commun. 284: 1168-1175, 2001.
Additional info: A synthetic peptide corresponding to a sequence at the C-terminal of human WNT9A(348-363aa, YVECRQCTQREEVYTC), different from the mouse sequence by one amino acid.
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