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Polyclonal Anti-rat IFN gamma

Cat no: RP1001

Polyclonal Anti-rat IFN gamma

Rabbit IgG polyclonal antibody for Interferon gamma (IFNG) detection. Tested with WB, IHC-P, ELISA, Neu, IP in Rat. \n

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SPECIFICATIONS

Price

240.00 USD

Catalog Number

RP1001

Size

100ug/vial

Applications

BNI, ELISA, IHC, IP, WB

Reactivities

Rat

Form

Lyophilized

Format

Each vial contains 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Gene Id

IFNG

References

1. Awad, M.; Pravica, V.; Perrey, C.; El Gamel, A.; Yonan, N.; Sinnott, P. J.; Hutchinson, I. V. CA repeat allele polymorphism in the first intron of the human interferon-gamma gene is associated with lung allograft fibrosis. Hum. Immunol. 60: 343-346, 1999. \n2. Szabo, S. J.; Sullivan, B. M.; Stemmann, C.; Satoskar, A. R.; Sleckman, B. P.; Glimcher, L. H. Distinct effects of T-bet in T(H)1 lineage commitment and IFN-gamma production in CD4 and CD8 T cells. Science 295: 338-342, 2002. \n3. Rossouw, M.; Nel, H. J.; Cooke, G. S.; van Helden, P. D.; Hoal, E. G. Association between tuberculosis and a polymorphic NF-kappa-B binding site in the interferon gamma gene. Lancet 361: 1871-1872, 2003. \n4. Nathan, C. F.; Murray, H. W.; Wiebe, M. E.; Rubin, B. Y. Identification of interferon-gamma as the lymphokine that activates human macrophage oxidative metabolism and antimicrobial activity. J. Exp. Med. 158: 670-689, 1983. \n5. Zohlnhofer, D.; Richter, T.; Neumann, F.-J.; Nuhrenberg, T.; Wessely, R.; Brandl, R.; Murr, A.; Klein, C. A.; Baeuerle, P. A. Transcriptome analysis reveals a role of interferon-gamma in human neointima formation. Molec. Cell 7: 1059-1069, 2001.

Swiss Prot

P01581

Storage Temp

\"At -20 degree C for one year. After reconstitution, at 4 degree C for one month. It can also be aliquotted and stored frozen at -20 degree C for a longer time.\nAvoid repeated freezing and thawing. \n\"\n

Additional Info

E. coli-derived rat IFNgamma recombinant protein (Position: 23-156).

Scientific Background

Interferon-gamma (IFN-gamma) is an inflammatory cytokine that has been implicated in the development of fibrosis in inflamed tissues. The production of IFN-gamma, which is under genetic control, can influence the development of fibrosis in lung allografts. IFN-gamma is also produced by natural killer (NK) cells and most prominently by CD8 cytotoxic T cells, and is vital for the control of microbial pathogens. Interferon gamma is believed to be crucial for host defence against many infections. Genetically determined variability in IFN-gamma and expression might be important for the development of tuberculosis. IFN-gamma activates human macrophage oxidative metabolism and antimicrobial activity. In addition to having antiviral activity, IFN-gamma has important immunoregulatory functions. IFN-gamma plays an important role in the control of neointima proliferation.

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Applications

WB

Reactivities

Hum

More info

Applications

ELISA, WB

Reactivities

Hum

More info

Applications

ELISA, IHC, WB

Reactivities

Hum

More info

Applications

ELISA, WB

Reactivities

Mouse

More info

Applications

ELISA, IHC, WB

Reactivities

Rat

More info

Applications

BNI, ELISA, IHC, IP, WB

Reactivities

Mouse

Conjugates

Unconj, Agarose, AP, Biotin, Gold, HRP, BE, GE, YE, OE, RE, FRE, NIR, ONFC

More info

Applications

BNI, ELISA, IHC, IP, WB

Reactivities

Rat

More info

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