

Supplier:
Boster ImmunoleaderCat no: RP1015
Polyclonal Anti-mouse IL-10
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SPECIFICATIONS
Price
240.00 USD
Catalog Number
RP1015
Size
100ug/vial
Applications
ELISA, WB
Reactivities
Mouse
Form
Lyophilized
Format
Each vial contains 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.
Gene Id
IL10
References
1. Eskdale J, Kube D, Tesch H, Gallagher G (1997). \"Mapping of the human IL10 gene and further characterization of the 5' flanking sequence\".
Swiss Prot
P18893
Storage Temp
\"At -20 degree C for one year. After reconstitution, at 4 degree C for one month. It can also be aliquotted and stored frozen at -20 degree C for a longer time.\nAvoid repeated freezing and thawing. \n\"\n
Additional Info
E. coli-derived mouse IL-10 recombinant protein (Position: S19-S178).
Scientific Background
Interleukin-10 (IL-10 or IL10), also known as human cytokine synthesis inhibitory factor (CSIF), is an anti-inflammatory cytokine. In humans IL-10 is encoded by the IL10 gene. It is capable of inhibiting synthesis of pro-inflammatory cytokines like IFN-gamma, IL-2, IL-3, TNFalpha and GM-CSF made by cells such as macrophages and regulatory T-cells.IL-10 also displays potent abilities to suppress the antigen presentation capacity of antigen presenting cells. Kim et al. (1992) showed that the mouse Il 10 gene contains 5 exons and spans about 5.2 kb of genomic DNA. Eskdale et al. (1997) mapped the IL10 gene to the junction between 1q31 and 1q32.
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