Polyclonal Anti-mouse IL-10

Rabbit IgG polyclonal antibody for Interleukin-10 (IL10) detection. Tested with WB, ELISA in Mouse. \n

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SPECIFICATIONS

Price

240.00 USD

Catalog Number

RP1015

Size

100ug/vial

Applications

ELISA, WB

Reactivities

Mouse

Form

Lyophilized

Format

Each vial contains 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Gene Id

IL10

References

1. Eskdale J, Kube D, Tesch H, Gallagher G (1997). \"Mapping of the human IL10 gene and further characterization of the 5' flanking sequence\".

Swiss Prot

P18893

Storage Temp

\"At -20 degree C for one year. After reconstitution, at 4 degree C for one month. It can also be aliquotted and stored frozen at -20 degree C for a longer time.\nAvoid repeated freezing and thawing. \n\"\n

Additional Info

E. coli-derived mouse IL-10 recombinant protein (Position: S19-S178).

Scientific Background

Interleukin-10 (IL-10 or IL10), also known as human cytokine synthesis inhibitory factor (CSIF), is an anti-inflammatory cytokine. In humans IL-10 is encoded by the IL10 gene. It is capable of inhibiting synthesis of pro-inflammatory cytokines like IFN-gamma, IL-2, IL-3, TNFalpha and GM-CSF made by cells such as macrophages and regulatory T-cells.IL-10 also displays potent abilities to suppress the antigen presentation capacity of antigen presenting cells. Kim et al. (1992) showed that the mouse Il 10 gene contains 5 exons and spans about 5.2 kb of genomic DNA. Eskdale et al. (1997) mapped the IL10 gene to the junction between 1q31 and 1q32.