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Polyclonal Anti-mouse TNF alpha

Cat no: RP1000

Polyclonal Anti-mouse TNF alpha

Rabbit IgG polyclonal antibody for Tumor necrosis factor (TNF) detection. Tested with WB, IHC-P, ELISA, Neu, IP in Mouse. \n

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SPECIFICATIONS

Price

240.00 USD

Catalog Number

RP1000

Size

100ug/vial

Applications

BNI, ELISA, IHC, IP, WB

Reactivities

Mouse

Conjugates

Unconj, Agarose, AP, Biotin, Gold, HRP, BE, GE, YE, OE, RE, FRE, NIR, ONFC

Form

Lyophilized

Format

Each vial contains 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Gene Id

TNF

References

1. Shirai, T., Yamaguchi, H., Ito, H., Todd, C. W., Wallace, R. B.Cloning and expression in Escherichia coli of the gene for human tumour necrosis factor.Nature 313: 803-806, 1985.\n2. Pennica, D., Nedwin, G. E., Hayflick, J. S., Seeburg, P. H., Derynck, R., Palladino, M. A., Kohr, W. J., Aggarwal, B. B., Goeddel, D. V.Human tumour necrosis factor: precursor structure, expression and homology to lymphotoxin.Nature 312: 724-729, 1984.

Swiss Prot

P06804

Storage Temp

\"At -20 degree C for one year. After reconstitution, at 4 degree C for one month. It can also be aliquotted and stored frozen at -20 degree C for a longer time.\nAvoid repeated freezing and thawing. \n\"\n

Additional Info

E. coli-derived mouse TNF alpha recombinant protein (Position: L80-L235).

Scientific Background

TNF(A)(Tumor Necrosis Factor alpha) gene encodes a multifunctional proinflammatory cytokine that belongs to the tumor necrosis factor (TNF) superfamily. This cytokine is mainly secreted by macrophages. It can bind to, and thus functions through its receptors TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. This cytokine is involved in the regulation of a wide spectrum of biological processes including cell proliferation, differentiation, apoptosis, lipid metabolism, and coagulation. This cytokine has been implicated in a variety of diseases, including autoimmune diseases, insulin resistance, and cancer. Knockout studies in mice also suggested the neuroprotective function of this cytokine.

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Applications

WB

Reactivities

Hum

More info

Applications

ELISA, WB

Reactivities

Hum

More info

Applications

ELISA, IHC, WB

Reactivities

Hum

More info

Applications

ELISA, WB

Reactivities

Mouse

More info

Applications

ELISA, IHC, WB

Reactivities

Rat

More info

Applications

BNI, ELISA, IHC, IP, WB

Reactivities

Mouse

Conjugates

Unconj, Agarose, AP, Biotin, Gold, HRP, BE, GE, YE, OE, RE, FRE, NIR, ONFC

More info

Applications

BNI, ELISA, IHC, IP, WB

Reactivities

Rat

More info

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