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Products Polyclonal Anti-WNT3A
| Catalogue number: | PA2120 |
| Price: | $200.00 |
| Reactivities: | Human, Mouse |
| Applications: | Western Blot |
| Size: | 100ug/vial |
| Gene: | WNT3A |
| Swiss prot: | P56704 |
| Form: | Lyophilized |
| Format: | Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3. |
| Storage temp: | At -20 degree C for one year. After reconstitution, at 4 degree C for one month. It can also be aliquotted and stored frozen at -20 degree C for a longer time.Avoid repeated freezing and thawing. |
| Scientific background: | Wingless-type MMIV integration site family, member 3A is a protein that in humans is encoded by the WNT3A gene. This gene is a member of the WNT gene family. The gene was assigned to human chromosome 1q42.13.These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. It encodes a protein showing 96% amino acid identity to mouse Wnt3A protein, and 84% to human WNT3 protein, another WNT gene product. |
| References: | 1. Aulehla, A., Herrmann, B. G. Segmentation in vertebrates: clock and gradient finally joined. Genes Dev. 18: 2060-2067, 2004. 2. Brack, A. S., Conboy, M. J., Roy, S., Lee, M., Kuo, C. J., Keller, C., Rando, T. A. Increased Wnt signaling during aging alters muscle stem cell fate and increases fibrosis. Science 317: 807-810, 2007. 3. Saitoh T, Hirai M, Katoh M (Jun 2001). "Molecular cloning and characterization of WNT3A and WNT14 clustered in human chromosome 1q42 region". Biochem Biophys Res Commun 284 (5): 1168 |
| Additional info: | A synthetic peptide corresponding to a sequence at the C-terminal of human WNT3A, identical to the related mouse sequence. |
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