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Products Polyclonal Anti-TRPV2
| Catalogue number: | PA1977 |
| Price: | $200.00 |
| Reactivities: | Human |
| Applications: | Immunohistochemistry, Immunohistochemistry - frozen, Western Blot |
| Size: | 100ug/vial |
| Gene: | TRPV2 |
| Swiss prot: | Q9Y5S1 |
| Form: | Lyophilized |
| Format: | Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3. |
| Storage temp: | At -20 degree C for one year. After reconstitution, at 4 degree C for one month. It can also be aliquotted and stored frozen at -20 degree C for a longer time.Avoid repeated freezing and thawing. |
| Scientific background: | TRPV2 (Transient Receptor Potential Cation Channel Subfamily V Member 2), also known as VRL1, is a protein that, in humans, is encoded by the TRPV1 gene. The International Radiation Hybrid Mapping Consortium mapped the TRPV2 gene to chromosome 17. This gene encodes an ion channel that is activated by high temperatures above 52 |
| References: | 1. Caterina, M. J., Rosen, T. A., Tominaga, M., Brake, A. J., Julius, D. A capsaicin-receptor homologue with a high threshold for noxious heat. Nature 398: 436-441, 1999. 2. Iwata, Y., Katanosaka, Y., Arai, Y., Shigekawa, M., Wakabayashi, S. Dominant-negative inhibition of Ca(2+) influx via TRPV2 ameliorates muscular dystrophy in animal models. Hum. Molec. Genet. 18: 824-834, 2009. |
| Additional info: | A synthetic peptide corresponding to a sequence at the N-terminal of human TRPV2. |
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