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Products Polyclonal Anti-TNFRSF1A
| Catalogue number: | PA1418 |
| Price: | $200.00 |
| Reactivities: | Mouse, Rat |
| Applications: | Western Blot |
| Size: | 100ug/vial |
| Gene: | TNFRSF1A |
| Swiss prot: | P25118 |
| Form: | Lyophilized |
| Format: | Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3. |
| Storage temp: | "At -20 degree C for one year. After reconstitution, at 4 degree C for one month. It can also be aliquotted and stored frozen at -20 degree C for a longer time. Avoid repeated freezing and thawing. " |
| Scientific background: | Tumor necrosis factor receptor superfamily member 1A (TNFRSF1A) is a protein that in humans is encoded by the TNFRSF1A gene. The protein encoded by this gene is a member of the Tumor necrosis factor receptor superfamily, which also contains TNFRSF1B. The TNFR1 gene is mapped to 12pter-cen. it encodes a protein of 455 amino acids. This receptor can activate the transcription factor NF-?B, mediate apoptosis, and function as a regulator of inflammation. |
| References: | 1. Baker E, Chen LZ, Smith CA, Callen DF, Goodwin R, Sutherland GR (Nov 1991). "Chromosomal location of the human tumor necrosis factor receptor genes". Cytogenet Cell Genet 57 (2-3): 117 |
| Additional info: | A synthetic peptide corresponding to a sequence at the N-terminal of mouse TNFRSF1A, different from the rat sequence by one amino acid. |
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