Supplier:
Boster ImmunoleaderCat no: PA2257
Polyclonal Anti-TNFAIP8L3
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SPECIFICATIONS
Price
200.00 USD
Catalog Number
PA2257
Size
100?g/vial
Applications
IHC, WB
Reactivities
Hum
Form
lyophilized
Format
Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.
Gene Id
TNFAIP8L3
Swiss Prot
Q5GJ75
Storage Temp
At -20 degree C for one year. After reconstitution, at 4 degree C for one month. It can also be aliquotted and stored frozen at -20 degree C for a longer time.Avoid repeated freezing and thawing.
Additional Info
A synthetic peptide corresponding to a sequence at the C-terminus of human TNFAIP8L3, different from the related mouse and rat sequences by two amino acids.
Scientific Background
TNFAIP8L3 belongs to the TNFAIP8 family. It acts as a negative mediator of apoptosis and may play a role in tumor progression. This gene suppresses the TNF-mediated apoptosis by inhibiting caspase-8 activity but not the processing of procaspase-8, subsequently resulting in inhibition of BID cleavage and caspase-3 activation.
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