
Supplier:
Boster ImmunoleaderCat no: PA1360
Polyclonal Anti-TGF alpha
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SPECIFICATIONS
Price
200.00 USD
Catalog Number
PA1360
Size
100ug/vial
Applications
WB
Reactivities
Hum
Form
Lyophilized
Format
Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.
Gene Id
TGFA
References
1.In vivo induction of massive proliferation, directed migration, and differentiation of neural cells in the adult mammalian brain.
Swiss Prot
P01135
Storage Temp
\"At -20 degree C for one year. After reconstitution, at 4 degree C for one month. It can also be aliquotted and stored frozen at -20 degree C for a longer time.\nAvoid repeated freezing and thawing. \n\"\n
Additional Info
A synthetic peptide corresponding to a sequence at the C-terminal of human TGFalpha, different from the mouse sequence by one amino acid.
Scientific Background
Transforming growth factor alpha (TGF-alpha) is upregulated in some human cancers. It is produced in macrophages, brain cells, and keratinocytes, and induces epithelial development. It is closely related to EGF, and can also bind to the EGF receptor with similar effects . TGFalpha stimulates neural cell proliferation in the adult injured brain. TGFalpha was cited in the 2001 NIH Stem Cell report to the U.S. Congress as promising evidence for the ability of adult stem cells to restore function in neurodegenerative disorders.
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