Polyclonal Anti-SLC2A9

Rabbit IgG polyclonal antibody for Solute carrier family 2, facilitated glucose transporter member 9 (SLC2A9) detection. Tested with WB in Human;Rat.

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SPECIFICATIONS

Price

200.00 USD

Catalog Number

PA2166

Size

100?g/vial

Applications

WB

Reactivities

Hum, Rat

Form

Lyophilized

Format

Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

Gene Id

SLC2A9

References

1. Anzai, N., Ichida, K., Jutabha, P., Kimura, T., Babu, E., Jin, C. J., Srivastava, S., Kitamura, K., Hisatome, I., Endou, H., Sakurai, H. Plasma urate level is directly regulated by a voltage-driven urate efflux transporter URATv1 (SLC2A9) in humans. J. Biol. Chem. 283: 26834-26838, 2008. Note: Erratum: J. Biol. Chem. 283: 32152 only, 2008.\n2. Preitner, F., Bonny, O., Laverriere, A., Rotman, S., Firsov, D., Da Costa, A., Metref, S., Thorens, B. Glut9 is a major regulator of urate homeostasis and its genetic inactivation induces hyperuricosuria and urate nephropathy. Proc. Nat. Acad. Sci. 106: 15501-15506, 2009. \n

Swiss Prot

Q9NRM0

Storage Temp

At -20 degree C for one year. After reconstitution, at 4 degree C for one month. It can also be aliquotted and stored frozen at -20 degree C for a longer time.Avoid repeated freezing and thawing.

Additional Info

A synthetic peptide corresponding to a sequence at the C-terminal of human SLC2A9, different from the related mouse and rat sequences by three amino acids.

Scientific Background

Solute carrier family 2, facilitated glucose transporter member 9, also known as SLC2A9, is a protein that in humans is encoded by the SLC2A9 gene. This gene encodes a member of the SLC2A facilitative glucose transporter family. Members of this family play a significant role in maintaining glucose homeostasis. This gene is mapped to 4p16.1. The encoded protein may play a role in the development and survival of chondrocytes in cartilage matrices. This gene transports urate and fructose. It may have a role in the urate reabsorption by proximal tubules. This gene also transports glucose at low rate.