Quick Search
Products Polyclonal Anti-SLC2A9
| Catalogue number: | PA2166 |
| Price: | $200.00 |
| Reactivities: | Human, Rat |
| Applications: | Western Blot |
| Size: | 100?g/vial |
| Gene: | SLC2A9 |
| Swiss prot: | Q9NRM0 |
| Form: | Lyophilized |
| Format: | Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3. |
| Storage temp: | At -20 degree C for one year. After reconstitution, at 4 degree C for one month. It can also be aliquotted and stored frozen at -20 degree C for a longer time.Avoid repeated freezing and thawing. |
| Scientific background: | Solute carrier family 2, facilitated glucose transporter member 9, also known as SLC2A9, is a protein that in humans is encoded by the SLC2A9 gene. This gene encodes a member of the SLC2A facilitative glucose transporter family. Members of this family play a significant role in maintaining glucose homeostasis. This gene is mapped to 4p16.1. The encoded protein may play a role in the development and survival of chondrocytes in cartilage matrices. This gene transports urate and fructose. It may have a role in the urate reabsorption by proximal tubules. This gene also transports glucose at low rate. |
| References: | 1. Anzai, N., Ichida, K., Jutabha, P., Kimura, T., Babu, E., Jin, C. J., Srivastava, S., Kitamura, K., Hisatome, I., Endou, H., Sakurai, H. Plasma urate level is directly regulated by a voltage-driven urate efflux transporter URATv1 (SLC2A9) in humans. J. Biol. Chem. 283: 26834-26838, 2008. Note: Erratum: J. Biol. Chem. 283: 32152 only, 2008. 2. Preitner, F., Bonny, O., Laverriere, A., Rotman, S., Firsov, D., Da Costa, A., Metref, S., Thorens, B. Glut9 is a major regulator of urate homeostasis and its genetic inactivation induces hyperuricosuria and urate nephropathy. Proc. Nat. Acad. Sci. 106: 15501-15506, 2009. |
| Additional info: | A synthetic peptide corresponding to a sequence at the C-terminal of human SLC2A9, different from the related mouse and rat sequences by three amino acids. |
Get the Best Promotions
