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Products Polyclonal Anti-SLC22A7
| Catalogue number: | PA2190 |
| Price: | $200.00 |
| Reactivities: | Human, Mouse, Rat |
| Applications: | Western Blot |
| Size: | 100?g/vial |
| Gene: | SLC22A7 |
| Swiss prot: | Q9Y694 |
| Form: | Lyophilized |
| Format: | Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3. |
| Storage temp: | At -20 degree C for one year. After reconstitution, at 4 degree C for one month. It can also be aliquotted and stored frozen at -20 degree C for a longer time.Avoid repeated freezing and thawing. |
| Scientific background: | Solute carrier family 22 member 7, also called SLC22A7 or OAT2 is a protein that in humans is encoded by the SLC22A7 gene. This gene is mapped to 6p21.1. The protein encoded by this gene is involved in the sodium-independent transport and excretion of organic anions, some of which are potentially toxic. The encoded protein is an integral membrane protein and appears to be localized to the basolateral membrane of the kidney. This gene transports prostaglandin E2, prostaglandin F2, tetracycline, bumetanide, estrone sulfate, glutarate, dehydroepiandrosterone sulfate, allopurinol, 5-fluorouracil, paclitaxel, L-ascorbic acid, salicylate, ethotrexate, and alpha-ketoglutarate. |
| References: | 1. Kok, L. D., Siu, S. S., Fung, K. P., Tsui, S. K., Lee, C. Y., Waye, M. M. Assignment of liver-specific organic anion transporter (SLC22A7) to human chromosome 6 bands p21.2-p21.1 using radiation hybrids. Cytogenet. Cell Genet. 88: 76-77, 2000. 2. Sun, W., Wu, R. R., van Poelje, P. D., Erion, M. D. Isolation of a family of organic anion transporters from human liver and kidney. Biochem. Biophys. Res. Commun. 283: 417-422, 2001. |
| Additional info: | A synthetic peptide corresponding to a sequence at the C-terminus of human SLC22A7, different from the related rat and mouse sequences by two amino acids. |
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