Catalogue number: |
PA1072 |
Price: |
$200.00 |
Reactivities: |
Human, Mouse, Rat |
Applications: |
Immunohistochemistry, Western Blot |
Size: |
100ug/vial |
Gene: |
SHH |
Swiss prot: |
Q15465 |
Form: |
Lyophilized |
Format: |
Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3. |
Storage temp: |
"At -20 degree C for one year. After reconstitution, at 4 degree C for one month. It can also be aliquotted and stored frozen at -20 degree C for a longer time.
Avoid repeated freezing and thawing.
"
|
Scientific background: |
The mouse, chicken, and zebrafish Shh homologs are highly conserved. SHH expression was not detected in adult tissues examined; however, it was expressed in fetal intestine, liver, lung, and kidney.
SHH gene is mapped to 7q. SHH mutations are not a frequent cause of isolated oral clefts. |
References: |
1. Tsukurov, O.; Boehmer, A.; Flynn, J.; Nicolai, J.-P.; Hamel, B. C. J.; Traill, S.; Zaleske, D.; Mankin, H. J.; Yeon, H.; Ho, C.; Tabin, C.; Seidman, J. G.; Seidman, C. : A complex bilateral polysyndactyly disease locus maps to chromosome 7q36. Nature Genet. 6: 282-286, 1994. |
Additional info: |
A synthetic peptide corresponding to a sequence at the N-terminal of human SHH, identical to the related mouse and rat sequences. |