Polyclonal Anti-RANK

Rabbit IgG polyclonal antibody for Tumor necrosis factor receptor superfamily member 11A (TNFRSF11A) detection. Tested with WB, IHC-P in Human. \n

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SPECIFICATIONS

Price

200.00 USD

Catalog Number

PA1382

Size

100ug/vial

Applications

IHC, WB

Reactivities

Hum

Form

Lyophilized

Format

Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

Gene Id

TNFRSF11A

References

1.Suda T, Takahashi N, Udagawa N, Jimi E, Gillespie MT, Martin TJ (1999). \"Modulation of osteoclast differentiation and function by the new members of the tumor necrosis factor receptor and ligand families\". Endocr. Rev. 20 (3): 345

Swiss Prot

Q9Y6Q6

Storage Temp

\"At -20 degree C for one year. After reconstitution, at 4 degree C for one month. It can also be aliquotted and stored frozen at -20 degree C for a longer time.\nAvoid repeated freezing and thawing. \n\"\n

Additional Info

A synthetic peptide corresponding to a sequence at the N-terminal of human RANK.

Scientific Background

Receptor Activator of Nuclear Factor ? B (RANK), also known as TRANCE Receptor, is a type I membrane protein that is expressed on the surface of osteoclasts and is involved in their activation upon ligand binding. RANK is also expressed on dendritic cells and facilitates immune signaling.RANKL (Receptor Activator for Nuclear Factor ? B Ligand) is found on the surface of stromal cells, osteoblasts, and T cells. By analysis of somatic cell and radiation hybrid panels, Anderson et al. (1997) mapped the RANK gene to 18q22.1.