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Products Polyclonal Anti-PPIG
| Catalogue number: | PA2152 |
| Price: | $200.00 |
| Reactivities: | Human, Mouse, Rat |
| Applications: | Western Blot |
| Size: | 100ug/vial |
| Gene: | PPIG |
| Swiss prot: | Q13427 |
| Form: | Lyophilized |
| Format: | Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3. |
| Storage temp: | At -20 degree C for one year. After reconstitution, at 4 degree C for one month. It can also be aliquotted and stored frozen at -20 degree C for a longer time.Avoid repeated freezing and thawing. |
| Scientific background: | Peptidyl-prolyl cis-trans isomerase G, also known as CASP10 or PPIase G, is an enzyme that in humans is encoded by the PPIG gene. The International Radiation Hybrid Mapping Consortium mapped the PPIG gene to chromosome 2q31.1. PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. This gene may be implicated in the folding, transport, and assembly of proteins. PPIG may play an important role in the regulation of pre-mRNA splicing. |
| References: | 1. Bourquin, J.-P., Stagljar, I., Meier, P., Moosmann, P., Silke, J., Baechi, T., Georgiev, O., Schaffner, W. A serine/arginine-rich nuclear matrix cyclophilin interacts with the C-terminal domain of RNA polymerase II. Nucleic Acids Res. 25: 2055-2061, 1997. 2. Nestel, F. P., Colwill, K., Harper, S., Pawson, T., Anderson, S. K. RS cyclophilins: identification of an NK-TR(1)-related cyclophilin. Gene 180: 151-155, 1996. |
| Additional info: | A synthetic peptide corresponding to a sequence at the N-terminal of human PPIG, identical to the related mouse and rat sequences. |
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