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Products Polyclonal Anti-MATN2
| Catalogue number: | PA1926 |
| Price: | $200.00 |
| Reactivities: | Human, Mouse, Rat |
| Applications: | Immunohistochemistry, Immunohistochemistry - frozen, Western Blot |
| Size: | 100ug/vial |
| Gene: | MATN2 |
| Swiss prot: | O00339 |
| Form: | Lyophilized |
| Format: | Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3. |
| Storage temp: | At -20 degree C for one year. After reconstitution, at 4 degree C for one month. It can also be aliquotted and stored frozen at -20 degree C for a longer time.Avoid repeated freezing and thawing. |
| Scientific background: | MATN2 (Matrilin-2) is a protein that in humans is encoded by the MATN2 gene. This gene encodes a member of the von Willebrand factor A domain containing protein family. This family of proteins is thought to be involved in the formation of filamentous networks in the extracellular matrices of various tissues. This protein contains five von Willebrand factor A domains. By fluorescence in situ hybridization, Muratoglu et al. (2000) mapped the MATN2 gene to chromosome 8q22. The specific function of this gene has not yet been determined. Two transcript variants encoding different isoforms have been found for this gene. |
| References: | 1. Deak, F., Piecha, D., Bachrati, C., Paulsson, M., Kiss, I. Primary structure and expression of matrilin-2, the closest relative of cartilage matrix protein within the von Willebrand factor type A-like module superfamily. J. Biol. Chem. 272: 9268-9274, 1997. 2. Muratoglu, S., Krysan, K., Balazs, M., Sheng, H., Zakany, R., Modis, L., Kiss, I., Deak, F. Primary structure of human matrilin-2, chromosome location of the MATN2 gene and conservation of an AT-AC intron in matrilin genes. Cytogenet. Cell Genet. 90: 323-327, 2000. |
| Additional info: | A synthetic peptide corresponding to a sequence at the C-terminal of human MATN2, identical to the related rat sequence and different from the related mouse sequence by one amino acid. |
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