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Products Polyclonal Anti-Layilin
| Catalogue number: | PA1686 |
| Price: | $200.00 |
| Reactivities: | Human, Mouse, Rat |
| Applications: | Immunohistochemistry, Western Blot |
| Size: | 100ug/vial |
| Gene: | LAYN |
| Swiss prot: | Q6UX15 |
| Form: | Lyophilized |
| Format: | Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3. |
| Storage temp: | At -20 degree C for one year. After reconstitution, at 4 degree C for one month. It can also be aliquotted and stored frozen at -20 degree C for a longer time.Avoid repeated freezing and thawing. |
| Scientific background: | Layilin is a widely expressed integral membrane hyaluronan receptor with homology to C-type lectins, originally identified as a binding partner of talin located in membrane ruffles. Layilin is recruited to membrane ruffles in cells induced to migrate in in vitro wounding experiments and in peripheral ruffles in spreading cells. The Layilin gene is mapped to 11q23.1. |
| References: | 1.Bono P, Cordero E, Johnson K, Borowsky M, Ramesh V, Jacks T, Hynes RO. Layilin, a cell surface hyaluronan receptor, interacts with merlin and radixin. Exp Cell Res. 2005 Aug 1;308(1):177-87. |
| Additional info: | A synthetic peptide corresponding to a sequence in the middle region of human Layilin, identical to the related rat and mouse sequences. |
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