Polyclonal Anti-IL-1 alpha

Rabbit IgG polyclonal antibody for Interleukin-1 alpha (IL1A) detection. Tested with WB, IHC-P in Mouse. \n

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SPECIFICATIONS

Price

200.00 USD

Catalog Number

PA1375

Size

100ug/vial

Applications

IHC, WB

Reactivities

Mouse

Form

Lyophilized

Format

Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

Gene Id

IL1A

References

1.Nicklin MJ, Weith A, Duff GW (Jun 1994). \"A physical map of the region encompassing the human interleukin-1 alpha, interleukin-1 beta, and interleukin-1 receptor antagonist genes\". Genomics 19 (2): 382

Swiss Prot

P01582

Storage Temp

\"At -20 degree C for one year. After reconstitution, at 4 degree C for one month. It can also be aliquotted and stored frozen at -20 degree C for a longer time.\nAvoid repeated freezing and thawing. \n\"\n

Additional Info

A synthetic peptide corresponding to a sequence at the C-terminal of mouse IL-1alpha.

Scientific Background

Interleukin-1 alpha (IL-1alpha) is a protein that in humans is encoded by the IL1A gene. The protein encoded by this gene is a cytokine of the interleukin-1 family. Interleukin-1 alpha possesses a wide spectrum of metabolic, physiological, haematopoietic activities, and plays one of the central roles in the regulation of the immune responses. It binds to the interleukin-1 receptor. Silver et al. (1990) showed that the mouse Il1a and Il1b genes are contained in a genomic fragment of about 70 kb. Further studies suggested that Il1b lies 5-prime to Il1a, that the 2 genes are oriented in the same direction, and that they are separated by about 50 kb.