Catalogue number: |
PA1043 |
Price: |
$200.00 |
Reactivities: |
Human, Mouse, Rat |
Applications: |
Immunohistochemistry, Western Blot |
Size: |
100ug/vial |
Gene: |
DNAJB1 |
Swiss prot: |
P25685 |
Form: |
Lyophilized |
Format: |
Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3. |
Storage temp: |
"At -20 degree C for one year. After reconstitution, at 4 degree C for one month. It can also be aliquotted and stored frozen at -20 degree C for a longer time.
Avoid repeated freezing and thawing.
"
|
Scientific background: |
The Hsp40 (heat shock protein with molecular size of approximately 40 kDa) is one of the mammalian homologues of bacterial DnaJ heat shock protein. Ohtsuka (1993) isolated a cDNA encoding a 40-kD heat-shock protein designated HSPF1. The deduced 340-amino acid HSPF1 protein is 34% identical to E. coli DnaJ and 34% and 36% identical to HSJ1 and HSJ2, respectively. HSPF1 gene spans over 7 kb and contains 3 exons and 2 introns. HSPF1 gene is mapped to chromosome 19p13.2. |
References: |
1. Hata, M.; Okumura, K.; Seto, M.; Ohtsuka, K. : Genomic cloning of a human heat shock protein 40 (Hsp40) gene (HSPF1) and its chromosomal localization to 19p13.2. Genomics 38: 446-449, 1996. |
Additional info: |
A synthetic peptide corresponding to a sequence at the C-terminal of human HSP40, different from the related mouse sequence by two amino acids, and from the related rat sequence by three amino acids. |