Catalogue number: |
PA1422 |
Price: |
$200.00 |
Reactivities: |
Human |
Applications: |
Immunohistochemistry, Western Blot |
Size: |
100ug/vial |
Gene: |
LGALS1 |
Swiss prot: |
P09382 |
Form: |
Lyophilized |
Format: |
Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3. |
Storage temp: |
"At -20 degree C for one year. After reconstitution, at 4 degree C for one month. It can also be aliquotted and stored frozen at -20 degree C for a longer time.
Avoid repeated freezing and thawing.
"
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Scientific background: |
Galectin-1 is a protein that in humans is encoded by the LGALS1 gene. Galectins belong to a family of related beta-galactoside-binding lectins, also referred to as S-type or S-Lac lectins. Its gene is mapped to 22q12-q13. Galectin-1 was expressed in a subset of slowly dividing subventricular zone astrocytes, which included the neural stem cells. It has been considered as an autocrine negative growth factor that regulates cell proliferation. |
References: |
1. Gitt MA, Barondes SH (February 1991). "Genomic sequence and organization of two members of a human lectin gene family". Biochemistry 30 (1): 82 |
Additional info: |
A synthetic peptide corresponding to a sequence at the C-terminal of human Galectin-1, different from the related rat and mouse sequences by one amino acid. |