Catalogue number: |
PA1035 |
Price: |
$200.00 |
Reactivities: |
Human, Mouse, Rat |
Applications: |
Immunohistochemistry, Western Blot |
Size: |
100ug/vial |
Gene: |
FSHR |
Swiss prot: |
P23945 |
Form: |
Liquid |
Format: |
Each vial contains 50% glycerol, 0.9mg NaCl, 0.2mg Na2HPO4. |
Storage temp: |
"At -20 degree C for one year. After reconstitution, at 4 degree C for one month. It can also be aliquotted and stored frozen at -20 degree C for a longer time.
Avoid repeated freezing and thawing.
"
|
Scientific background: |
Follicle-stimulating hormone is essential for normal reproductive function in males and females. FSHR gene encodes a 695-amino acid predicted protein. Amino acid sequence similarity is high in comparison with the previously described rat gene, ranging from 82% in exon 9 to 100% in exon 3. Human FSH receptor is mapped to chromosome 2p21. |
References: |
1. Gromoll, J.; Ried, T.; Holtgreve-Grez, H.; Nieschlag, E.; Gudermann, T. : Localization of the human FSH receptor to chromosome 2p21 using a genomic probe comprising exon 10. J. Molec. Endocr. 12: 265-271, 1994.
2. Rousseau-Merck, M. F.; Atger, M.; Loosfelt, H.; Milgrom, E.; Berger, R. : The chromosomal localization of the human follicle-stimulating hormone receptor gene (FSHR) on 2p21-p16 is similar to that of the luteinizing hormone receptor gene. Genomics 15: 222-224, 1993. |
Additional info: |
A synthetic peptide corresponding to a sequence at the N-terminal of human FSHR, different from the related rat and mouse sequences by three amino acids. |