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Products Polyclonal Anti-FGF9
| Catalogue number: | PA1453 |
| Price: | $200.00 |
| Reactivities: | Human, Mouse, Rat |
| Applications: | Immunohistochemistry, Western Blot |
| Size: | 100ug/vial |
| Gene: | FGF9 |
| Swiss prot: | P31371 |
| Form: | Lyophilized |
| Format: | Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3. |
| Storage temp: | "At -20 degree C for one year. After reconstitution, at 4 degree C for one month. It can also be aliquotted and stored frozen at -20 degree C for a longer time. Avoid repeated freezing and thawing. " |
| Scientific background: | FGF 9, Fibroblast growth factor 9, is a protein that in humans is encoded by the FGF9 gene. The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. The FGF 9 gene contains 3 exons. By radioactive chromosomal in situ hybridization, the FGF 9 gene is mapped to chromosome 13q11-q12. This protein was isolated as a secreted factor that exhibits a growth-stimulating effect on cultured glial cells. In nervous system, this protein is produced mainly by neurons and may be important for glial cell development. Expression of the mouse homolog of this gene was found to be dependent on Sonic hedgehog (Shh) signaling. |
| References: | 1. Mariani, F. V., Ahn, C. P., Martin, G. R.Genetic evidence that FGFs have an instructive role in limb proximal-distal patterning.Nature 453: 401-405, 2008. 2. Mattei, M.-G., Penault-Llorca, F., Coulier, F., Birnbaum, D.The human FGF 9 gene maps to chromosomal region 13q11-q12.Genomics 29: 811-812, 1995. 3. Sun, X., Lewandoski, M., Meyers, E. N., Liu, Y.-H., Maxson, R. E., Jr., Martin, G. R.Conditional inactivation of Fgf4 reveals complexity of signalling during limb bud development.Nature Genet. 25: 83-86, 2000. |
| Additional info: | A synthetic peptide corresponding to a sequence in the middle region of human FGF9, identical to the related mouse and rat sequence. |
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