Catalogue number: |
PA1028 |
Price: |
$200.00 |
Reactivities: |
Human |
Applications: |
Western Blot |
Size: |
100ug/vial |
Gene: |
CRP |
Swiss prot: |
P02741 |
Form: |
Lyophilized |
Format: |
Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3. |
Storage temp: |
"At -20 degree C for one year. After reconstitution, at 4 degree C for one month. It can also be aliquotted and stored frozen at -20 degree C for a longer time.
Avoid repeated freezing and thawing.
"
|
Scientific background: |
C Reactive Protein (CRP) is a major acute phase reactant synthesized primarily in the liver hepatocytes. It is composed of 5 identical, 21,500-molecular weight subunits. CRP mediates activities associated with preimmune nonspecific host resistance. CRP shows the strongest association with cardiovascular events. It is detectable on the surface of about 4% of normal peripheral blood lymphocytes. Acute phase reactant CRP is produced in the liver. |
References: |
1. Kilpatrick, J. M.; Volanakis, J. E. : Molecular genetics, structure, and function of C-reactive protein. Immun. Res. 10: 43-53, 1991.
2. Kuta, A. E.; Baum, L. L. : C-reactive protein is produced by a small number of normal human peripheral blood lymphocytes. J. Exp. Med. 164: 321-326, 1986.
3. Oliveira, E. B.; Gotshlich, E. C.; Liu, T. : Primary structure of human C-reactive protein. J. Biol. Chem. 254: 489-502, 1979. |
Additional info: |
A synthetic peptide corresponding to a sequence at the C-terminal of human CRP. |