Catalogue number: | PA1876 |
Price: | $200.00 |
Reactivities: | Mouse, Rat |
Applications: | Western Blot |
Size: | 100ug/vial |
Gene: | CDKN1C |
Swiss prot: | P49919 |
Form: | Lyophilized |
Format: | Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3. |
Storage temp: | At -20 degree C for one year. After reconstitution, at 4 degree C for one month. It can also be aliquotted and stored frozen at -20 degree C for a longer time.Avoid repeated freezing and thawing. |
Scientific background: | CDKN1C(Cyclin-dependent kinase inhibitor 1C) also called p57(KIP2) or KIP2, is |
References: | 1. Diaz-Meyer, N., Yang, Y., Sait, S. N., Maher, E. R., Higgins, M. J. Alternative mechanisms associated with silencing of CDKN1C in Beckwith-Wiedemann syndrome. J. Med. Genet. 42: 648-655, 2005. 2. Matsuoka, S., Edwards, M. C., Bai, C., Parker, S., Zhang, P., Baldini, A., Harper, J. W., Elledge, S. J.p57(KIP2), a structurally distinct member of the p21(CIP1) Cdk inhibitor family, is a candidate tumor suppressor gene. Genes Dev. 9: 650-662, 1995. 3. O'Keefe, D., Dao, D., Zhao, L., Sanderson, R., Warburton, D., Weiss, L., Anyane-Yeboa, K., Tycko, B. Coding mutations in p57(KIP2) are present in some cases of Beckwith-Wiedemann syndrome but are rare or absent in Wilms tumors. Am. J. Hum. Genet. 61: 295-303, 1997. |
Additional info: | A synthetic peptide corresponding to a sequence at the N-terminal of mouse , identical to the related rat sequence, and different from the related human sequence by two amino acids. |