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Polyclonal Anti-CDKN1C

Cat no: PA1876


Supplier: Boster Immunoleader
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Rabbit IgG polyclonal antibody for Cyclin-dependent kinase inhibitor 1C (CDKN1C) detection. Tested with WB in Mouse;Rat.
Catalogue number: PA1876
Price: $200.00
Reactivities: Mouse, Rat
Applications: Western Blot
Size: 100ug/vial
Gene: CDKN1C
Swiss prot: P49919
Form: Lyophilized
Format: Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.
Storage temp: At -20 degree C for one year. After reconstitution, at 4 degree C for one month. It can also be aliquotted and stored frozen at -20 degree C for a longer time.Avoid repeated freezing and thawing.
Scientific background: CDKN1C(Cyclin-dependent kinase inhibitor 1C) also called p57(KIP2) or KIP2, is
References: 1. Diaz-Meyer, N., Yang, Y., Sait, S. N., Maher, E. R., Higgins, M. J. Alternative mechanisms associated with silencing of CDKN1C in Beckwith-Wiedemann syndrome. J. Med. Genet. 42: 648-655, 2005. 2. Matsuoka, S., Edwards, M. C., Bai, C., Parker, S., Zhang, P., Baldini, A., Harper, J. W., Elledge, S. J.p57(KIP2), a structurally distinct member of the p21(CIP1) Cdk inhibitor family, is a candidate tumor suppressor gene. Genes Dev. 9: 650-662, 1995. 3. O'Keefe, D., Dao, D., Zhao, L., Sanderson, R., Warburton, D., Weiss, L., Anyane-Yeboa, K., Tycko, B. Coding mutations in p57(KIP2) are present in some cases of Beckwith-Wiedemann syndrome but are rare or absent in Wilms tumors. Am. J. Hum. Genet. 61: 295-303, 1997.
Additional info: A synthetic peptide corresponding to a sequence at the N-terminal of mouse , identical to the related rat sequence, and different from the related human sequence by two amino acids.