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Products Polyclonal Anti-CD133
| Catalogue number: | PA1217 |
| Price: | $200.00 |
| Reactivities: | Human, Mouse, Rat |
| Applications: | Immunohistochemistry, Western Blot |
| Size: | 100ug/vial |
| Gene: | PROM1 |
| Swiss prot: | O43490 |
| Form: | Lyophilized |
| Format: | Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3. |
| Storage temp: | "At -20 degree C for one year. After reconstitution, at 4 degree C for one month. It can also be aliquotted and stored frozen at -20 degree C for a longer time. Avoid repeated freezing and thawing. " |
| Scientific background: | CD133, is a glycoprotein also known in humans and rodents as Prominin 1 (PROM1). It is the founding member of pentaspan transmembrane glycoproteins (5-transmembrane, 5-TM), which specifically localizes to cellular protrusions. The gene of CD133 is located in 4p15.3. And most of the CD133 gene is contained in 23 exons distributed over more than 50 kb of genomic sequence. CD133 is expressed in hematopoietic stem cells, endothelial progenitor cells, glioblastomas, neuronal and glial stem cells and some other cell types. |
| References: | 1. Corbeil D, Fargeas C, Huttner W (2001). "Rat prominin, like its mouse and human orthologues, is a pentaspan membrane glycoprotein". Biochem Biophys Res Commun 285 (4): 939 |
| Additional info: | A synthetic peptide corresponding to a sequence at the N-terminal of human CD133. |
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