Polyclonal Anti-ATXN1

Rabbit IgG polyclonal antibody for Ataxin-1 (ATXN1) detection. Tested with WB in Human.

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SPECIFICATIONS

Price

200.00 USD

Catalog Number

PA2097

Size

100ug/vial

Applications

WB

Reactivities

Hum

Form

Lyophilized

Format

Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

Gene Id

ATXN1

References

1. Volz A, Fonatsch C, Ziegler A (Jun 1992). \"Regional mapping of the gene for autosomal dominant spinocerebellar ataxia (SCA1) by localizing the closely linked D6S89 locus to 6p24.2----p23.05\". Cytogenet Cell Genet 60 (1): 37

Swiss Prot

P54253

Storage Temp

At -20 degree C for one year. After reconstitution, at 4 degree C for one month. It can also be aliquotted and stored frozen at -20 degree C for a longer time.Avoid repeated freezing and thawing.

Additional Info

A synthetic peptide corresponding to a sequence in the middle region of human ATXN1, different from the related rat sequence by two amino acids, and from the related mouse sequence by three amino acids.

Scientific Background

Ataxin-1 is a protein that in humans is encoded by the ATXN1 gene. The ATXN1 gene had been mapped to 6p23 by in situ hybridization. Ataxin-1 (ATXN1), a causative factor for spinocerebellar ataxia type 1 (SCA1), and the related Brother of ATXN1 (BOAT1) are human proteins involved in transcriptional repression. ATXN1 and BOAT1 might participate in several Notch-controlled developmental and pathological processes.