Catalogue number: |
PA1511 |
Price: |
$200.00 |
Reactivities: |
Human |
Applications: |
Western Blot |
Size: |
100ug/vial |
Gene: |
AQP8 |
Swiss prot: |
O94778 |
Form: |
Lyophilized |
Format: |
Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3. |
Storage temp: |
"At -20 degree C for one year. After reconstitution, at 4 degree C for one month. It can also be aliquotted and stored frozen at -20 degree C for a longer time.
Avoid repeated freezing and thawing.
"
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Scientific background: |
AQP8, also known as Aquaporin-8, is a protein that in humans is encoded by the AQP8 gene. Aquaporin 8 (AQP8) is a water channel protein. Aquaporins are a family of small integral membrane proteins related to the major intrinsic protein (MIP or AQP0). Aquaporin 8 mRNA is found in pancreas and colon but not other tissues. The AQP8 gene contains 6 exons. It is mapped to chromosome 16p12. Northern blot analysis of human tissues detected a 1.35-kb AQP8 mRNA only in pancreas and colon. |
References: |
1. Huang J, et al. Expression of aquaporin 8 in human fetal membrane and placenta of idiopathic polyhydramnios]. Zhonghua Fu Chan Ke Za Zhi, 2009 Jan.
2. Larocca MC, et al. Knockdown of hepatocyte aquaporin-8 by RNA interference induces defective bile canalicular water transport. Am J Physiol Gastrointest Liver Physiol, 2009 Jan.
3. Zhu X, et al. The expression of aquaporin 8 and aquaporin 9 in fetal membranes and placenta in term pregnancies complicated by idiopathic polyhydramnios. Early Hum Dev, 2010 Oct.
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Additional info: |
A synthetic peptide corresponding to a sequence at the N-terminal of human AQP8. |