Catalogue number: |
PA1487 |
Price: |
$200.00 |
Reactivities: |
Human, Mouse, Rat |
Applications: |
Western Blot |
Size: |
100ug/vial |
Gene: |
ANGPTL1 |
Swiss prot: |
O95841 |
Form: |
Lyophilized |
Format: |
Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3. |
Storage temp: |
"At -20 degree C for one year. After reconstitution, at 4 degree C for one month. It can also be aliquotted and stored frozen at -20 degree C for a longer time.
Avoid repeated freezing and thawing.
"
|
Scientific background: |
ANGPTL1, Angiopoietin-related protein 1, is a protein that in humans is encoded by the ANGPTL1 gene. Angiopoietins are members of the vascular endothelial growth factor family and the only known growth factors largely specific for vascular endothelium. Angiopoietin-1, angiopoietin-2, and angiopoietin-4 participate in the formation of blood vessels. The protein encoded by this gene is another member of the angiopoietin family that is widely expressed in adult tissues with mRNA levels highest in highly vascularized tissues. This protein was found to be a secretory protein that does not act as an endothelial cell mitogen in vitro. ANGPTL1 is widely expressed in human adult tissues as a major 3.0-kb transcript and a less abundant 4.0-kb transcript. |
References: |
1. Kim, I., Kwak, H. J., Ahn, J. E., So, J.-N., Liu, M., Koh, K. N., Koh, G. Y.Molecular cloning and characterization of a novel angiopoietin family protein, angiopoietin-3.FEBS Lett. 443: 353-356, 1999. |
Additional info: |
A synthetic peptide corresponding to a sequence at the C-terminal of human ANGPTL1, identical to the related rat and mouse sequences. |