Catalogue number: |
MA1099 |
Price: |
$200.00 |
Reactivities: |
Human, Rat, Rabbit |
Applications: |
Western Blot |
Size: |
100ug/vial |
Gene: |
Human(7166), Mouse(21990), Rat(24848), Human(121278), Mouse(216343), Rat(317675) |
Swiss prot: |
Human(P17752), Mouse(P17532), Rat(P09810), Human(Q8IWU9), Mouse(Q8CGV2), Rat(Q8CGU9) |
Form: |
Lyophilized |
Format: |
1.2% sodium acetate or neutral PBS. If 1ml of PBS is used, the antibody concentration will be 100ug/ml. |
Target synonym: |
TPH; TPRH; TRPH; ADHD7; NTPH
|
Storage temp: |
At -20 degree C for one year. After reconstitution, at 4 degree C for one month. It can also be aliquotted and stored frozen at -20 degree C for a longer time. Avoid repeated freezing and thawing. |
Primary protein: |
Tryptophan 5-hydroxylase 1; Tryptophan 5-hydroxylase 2
|
Scientific background: |
Tryptophan hydroxylase is the rate-limiting enzyme in the synthesis of serotonin (5-hydroxytryptamine, or 5HT). Tryptophan hydroxylase\atalyzes the biopterin-dependent monooxygenation of tryptophan to5-hydroxytryptophan (5HT), which is subsequently decarboxylated to form the neurotransmitter serotonin. Human tryptophan hydroxylase (TPH) is mapped to chromosome 11p15.3-p14 by in situ hybridization. |