Monoclonal Anti-S-100 (beta-subunit)

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SPECIFICATIONS

Price

200.00 USD

Catalog Number

MA1088

Size

100ug/vial

Applications

IHC, WB

Reactivities

Hum, Rat, Rabbit

Form

Lyophilized

Format

1.2% sodium acetate or neutral PBS. If 1ml of PBS is used, the antibody concentration will be 100ug/ml.

Gene Id

Human(6285), Mouse(20203), Rat(25742)

Swiss Prot

Human(P04271), Mouse(P50114), Rat(P04631)

Storage Temp

At -20 degree C for one year. After reconstitution, at 4 degree C for one month. It can also be aliquotted and stored frozen at -20 degree C for a longer time. Avoid repeated freezing and thawing.

Target Synonym

NEF; S100; S100-B; S100beta; S100 calcium binding protein, beta (neural); S-100 protein beta chain; S-100 protein subunit beta

Primary Protein

Protein S100-B

Scientific Background

S100 protein is a 21,000-Da component first isolated from brain by Moore (1965). Immunocytochemical studies demonstrated that S100 protein is produced by a wide variety of normal and neoplastic cells of mesodermal, neuroectodermal, and epithelial origin (Herrera et al., 1988). The S100 molecule is a dimer; thus there are 3 forms of S100: alpha-alpha, known as S-100a(0); alpha-beta, known as S-100a; and beta-beta, known as S-100b. S100 genes are clustered on human chromosome 1q21. S-100 protein expression by primary and metastatic adenocarcinomas.