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Products Monoclonal Anti-Paxillin
| Catalogue number: | MA1080 |
| Price: | $200.00 |
| Reactivities: | Human, Mouse, Rat, Chicken/Bird |
| Applications: | Immunocytochemistry, Western Blot |
| Size: | 100ug/vial |
| Gene: | Human(5829), Mouse(19303), Rat(360820) |
| Swiss prot: | Human(P49023), Mouse(Q8VI36), Rat(Q66H76) |
| Form: | Lyophilized |
| Format: | 1.2% sodium acetate or neutral PBS. If 1ml of PBS is used, the antibody concentration will be 100ug/ml. |
| Storage temp: | At -20 degree C for one year. After reconstitution, at 4 degree C for one month. It can also be aliquotted and stored frozen at -20 degree C for a longer time. Avoid repeated freezing and thawing. |
| Primary protein: | Paxillin |
| Scientific background: | The paxillin gene can be alternatively spliced to include 1 of 2 alternative exons, generating beta and gamma isoforms. Paxillin is a 68-kDa focal adhesion protein that is phosphorylated on tyrosine residues in fibroblasts in response to transformation by v-src, treatment with platelet-derived growth factor, or cross-linking of integrins. The 68-kD protein (paxillin) is a cytoskeletal component that localizes to the focal adhesions at the ends of actin stress fibers in chicken embryo fibroblasts. It is also present in the focal adhesions of Madin-Darby bovine kidney (MDBK) epithelial cells but is absent, like talin, from the cell-cell adherens junctions of these cells. |
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