Catalogue number: |
MA1079 |
Price: |
$200.00 |
Reactivities: |
Human, Mouse, Rat, Chicken/Bird, Rabbit |
Applications: |
Immunohistochemistry, Western Blot |
Size: |
100ug/vial |
Gene: |
Human(999), Mouse(12550), Rat(83502), Human(1000), Mouse(12558), Rat(83501), Human(1001), Mouse(12560), Rat(116777) |
Swiss prot: |
Human(P12830), Mouse(P09803), Rat(Q9R0T4), Human(P19022), Mouse(P15116), Rat(Q9Z1Y3), Human(P22223), Mouse(P10287), Rat(F1LMI3) |
Form: |
Lyophilized |
Format: |
1.2% sodium acetate or neutral PBS. If 1ml of PBS is used, the antibody concentration will be 100ug/ml. |
Target synonym: |
UVO; CDHE; ECAD; LCAM; Arc-1; CD324; CDHN; NCAD; CD325; CDw325; CDHP; HJMD; PCAD
|
Storage temp: |
At -20 degree C for one year. After reconstitution, at 4 degree C for one month. It can also be aliquotted and stored frozen at -20 degree C for a longer time. Avoid repeated freezing and thawing. |
Primary protein: |
Cadherin-1; Cadherin-2; Cadherin-3 |
Scientific background: |
Cadherins are calcium-dependent cell-cell adhesion molecules that mediate cell-cell binding in a homophilic manner. They play an important role in the growth and development of cells via the mechanisms of control of tissue architecture and the maintenance of tissue integrity. Cadherin expression is regulated spatially as well as temporally. Cadherins are thought to play an important role in development and maintenance of tissues through selective cell-cell adhesion activity and may be involved also in the invasion and metastasis of malignant tumors. Cadherin regulates dendritic spine morphogenesis. A cadherin gene cluster is mapped to a region of chromosome 5 subject to frequent allelic loss in carcinoma. |