Catalogue number: |
MA1071 |
Price: |
$200.00 |
Reactivities: |
Human, Mouse, Rat |
Applications: |
Immunohistochemistry, Immunohistochemistry - frozen, Western Blot |
Size: |
100ug/vial |
Gene: |
Human(4744), Mouse(380684), Rat(24587) |
Swiss prot: |
Human(P12036), Mouse(P19246), Rat(P16884) |
Form: |
Lyophilized |
Format: |
1.2% sodium acetate or neutral PBS. If 1ml of PBS is used, the antibody concentration will be 100ug/ml. |
Target synonym: |
NFH; KIAA0845; 200 kDa neurofilament protein; Neurofilament triplet H protein |
Storage temp: |
At -20 degree C for one year. After reconstitution, at 4 degree C for one month. It can also be aliquotted and stored frozen at -20 degree C for a longer time. Avoid repeated freezing and thawing. |
Primary protein: |
Neurofilament heavy polypeptide |
Scientific background: |
Neurofilaments are composed of 3 neuron-specific proteins with apparent molecular masses of 68 kD (NFL), 125 kD (NFM), and 200 kD (NFH) on SDS-gel electrophoresis. Genomic clones for the largest human neurofilament protein (NF-H) were isolated, the intron/exon boundaries mapped and the entire protein-coding regions (exons) sequenced. mutations in neurofilaments have been linked to some forms of Charcot-Marie-Tooth disease (CMT). |