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Products Monoclonal Anti-Nebulin
| Catalogue number: | MA1069 |
| Price: | $200.00 |
| Reactivities: | Chicken/Bird |
| Applications: | Western Blot |
| Size: | 100ug/vial |
| Gene: | Human(4703), Mouse(17996 ), Rat(311029 ), Chicken(374027) |
| Swiss prot: | Human(P20929) |
| Form: | Lyophilized |
| Format: | 1.2% sodium acetate or neutral PBS. If 1ml of PBS is used, the antibody concentration will be 100ug/ml. |
| Target synonym: | NEM2; NEB177D |
| Storage temp: | At -20 degree C for one year. After reconstitution, at 4 degree C for one month. It can also be aliquotted and stored frozen at -20 degree C for a longer time. Avoid repeated freezing and thawing. |
| Primary protein: | Nebulin |
| Scientific background: | Nebulin is a giant protein component of the cytoskeletal matrix that coexists with the thick and thin filaments within the sarcomeres of skeletal muscle. In most vertebrates, nebulin accounts for 3 to 4% of the total myofibrillar protein and its size varies from 600 to 800 kD in a manner that is tissue-, species-, and developmental stage-specific. The nebulin gene contains 183 exons in a 249-kb genomic region. Nebulin is mapped to chromosome 2. Nebulin is a giant filamentous protein specific for vertebrate skeletal muscles. Mutations in the nebulin gene associated with autosomal recessive nemaline myopathy. |
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