Monoclonal Anti-N-Cadherin

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SPECIFICATIONS

Price

200.00 USD

Catalog Number

MA1067

Size

100ug/vial

Applications

IHC-Fr, WB

Reactivities

Hum, Mouse, Rat, Ch/Bird, Rabbit

Form

Lyophilized

Format

1.2% sodium acetate or neutral PBS. If 1ml of PBS is used, the antibody concentration will be 100ug/ml.

Gene Id

Human(1000), Mouse(12558), Rat(83501)

Swiss Prot

Human(P19022), Mouse(P15116), Rat(Q9Z1Y3)

Storage Temp

At -20 degree C for one year. After reconstitution, at 4 degree C for one month. It can also be aliquotted and stored frozen at -20 degree C for a longer time. Avoid repeated freezing and thawing.

Target Synonym

CDHN; NCAD; CD325; CDw325; Neural cadherin\n \n

Primary Protein

Cadherin-2

Scientific Background

N-cadherin (NCAD) is a member of the cadherin cell-cell adhesion receptor family that includes P-, E-, and R-cadherin and liver cell adhesion molecule (L-CAM). N-Cadherin,, also known as Cadherin-2, encodes a 907-amino acid protein that includes a 159-amino acid signal sequence. Human and mouse nucleotide sequences are 96% identical. Mouse Ncad gene consists of 16 exons dispersed over more than 200 kb of genomic DNA. Human N-cadherin gene contains 16 exons and its sequence is highly similar to both the mouse NCAD gene (including the large first and second introns) and other cadherin genes. N-cadherin is mapped to 18q11.2. Cadherin regulates dendritic spine morphogenesis.