Monoclonal Anti-Insulin

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SPECIFICATIONS

Price

200.00 USD

Catalog Number

MA1052

Size

100ug/vial

Applications

IHC

Reactivities

Hum, Rat, Rabbit

Form

Lyophilized

Format

1.2% sodium acetate or neutral PBS. If 1ml of PBS is used, the antibody concentration will be 100ug/ml.

Gene Id

Human(3630), Mouse(16334), Rat(24509)

Swiss Prot

Human(P01308), Mouse(P01326), Rat(P01323)

Storage Temp

At -20 degree C for one year. After reconstitution, at 4 degree C for one month. It can also be aliquotted and stored frozen at -20 degree C for a longer time. Avoid repeated freezing and thawing.

Target Synonym

PROINSULIN; ILPR; IRDN; IDDM2; MODY10; Insulin2; Ins-2\n

Primary Protein

Insulin

Scientific Background

Insulin, synthesized by the beta cells of the islets of Langerhans, consists of 2 dissimilar polypeptide chains, A and B, which are linked by 2 disulfide bonds. The insulin gene contains 3 exons and 2 introns; exon 2 encodes the signal peptide, the B chain, and part of the C peptide, while exon 3 encodes the remainder of the C peptide and the A chain. Localization of the human insulin gene to the distal end of the short arm of chromosome 11. Harper et al. (1981) and Harper and Saunders (1981) assigned the insulin gene to 11p15.5 by in situ hybridization.