Monoclonal Anti-HSP70

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SPECIFICATIONS

Price

200.00 USD

Catalog Number

MA1050

Size

100ug/vial

Applications

IHC, IHC-Fr, WB

Reactivities

Hum, Rat, Bov, Rabbit

Form

Lyophilized

Format

1.2% sodium acetate or neutral PBS. If 1ml of PBS is used, the antibody concentration will be 100ug/ml.

Gene Id

Human(3303), Mouse(193740), Rat(24472), Human(3304), Mouse(15511), Rat(294254)

Swiss Prot

Human(P08107), Mouse(Q61696), Rat(Q07439), Mouse(P17879)

Storage Temp

At -20 degree C for one year. After reconstitution, at 4 degree C for one month. It can also be aliquotted and stored frozen at -20 degree C for a longer time. Avoid repeated freezing and thawing.

Target Synonym

HSPA1; Hsp70-1; Hsp70-2; Heat shock 70 kDa protein 1/2\n

Primary Protein

Heat shock 70 kDa protein 1A/1B

Scientific Background

Heat-shock proteins, or stress proteins, are expressed in response to heat shock and a variety of other stress stimuli including oxidative free radicals and toxic metal ions. Sargent et al. (1989) identified a duplicated HSP70 locus in the class III region of the major histocompatibility complex on 6p21.3. A duplicated locus encoding the major heat shock-induced protein HSP70 is located in the major histocompatibility complex (MHC) class III region 92 kilobases (kb) telomeric to the C2 gene. The 70-kd mammalian heat shock proteins are structurally and functionally related to the uncoating protein that releases clathrin triskelia from coated vesicles.