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Products Monoclonal Anti-HSP60
| Catalogue number: | MA1049 |
| Price: | $200.00 |
| Reactivities: | Human, Rat, Chicken/Bird |
| Applications: | Immunohistochemistry, Western Blot |
| Size: | 100ug/vial |
| Gene: | Human(3329), Mouse(15510), Rat(63868) |
| Swiss prot: | Human(P10809), Mouse(P63038), Rat(P63039) |
| Form: | Lyophilized |
| Format: | 1.2% sodium acetate or neutral PBS. If 1ml of PBS is used, the antibody concentration will be 100ug/ml. |
| Target synonym: | SPG13; GROEL; CPN60; HuCHA60; spastic paraplegia 13 (autosomal dominant); CHAPERONIN, 60-KD; Mitochondrial matrix protein P1; P60 lymphocyte protein; Heat shock protein 60; 60 kDa chaperonin; Chaperonin 60 |
| Storage temp: | At -20 degree C for one year. After reconstitution, at 4 degree C for one month. It can also be aliquotted and stored frozen at -20 degree C for a longer time. Avoid repeated freezing and thawing. |
| Primary protein: | 60 kDa heat shock protein, mitochondrial |
| Scientific background: | Heat shock 60KD protein (HSP60) is a member of the chaperonin class of protein factors and the nuclear encoded mitochondrial HSP60 is required for the assembly into oligomeric complexes of proteins imported into the mitochondrial matrix. HSP60 is linked head to head comprising approximately 17 kb and consist of 12 exons. HSP60 is a self-molecule, it can downregulate adaptive immune responses by upregulating Tregs innately through TLR2 signaling. |
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