Monoclonal Anti-HSP60

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SPECIFICATIONS

Price

200.00 USD

Catalog Number

MA1049

Size

100ug/vial

Applications

IHC, WB

Reactivities

Hum, Rat, Ch/Bird

Form

Lyophilized

Format

1.2% sodium acetate or neutral PBS. If 1ml of PBS is used, the antibody concentration will be 100ug/ml.

Gene Id

Human(3329), Mouse(15510), Rat(63868)

Swiss Prot

Human(P10809), Mouse(P63038), Rat(P63039)

Storage Temp

At -20 degree C for one year. After reconstitution, at 4 degree C for one month. It can also be aliquotted and stored frozen at -20 degree C for a longer time. Avoid repeated freezing and thawing.

Target Synonym

SPG13; GROEL; CPN60; HuCHA60; spastic paraplegia 13 (autosomal dominant); CHAPERONIN, 60-KD; Mitochondrial matrix protein P1; P60 lymphocyte protein; Heat shock protein 60; 60 kDa chaperonin; Chaperonin 60

Primary Protein

60 kDa heat shock protein, mitochondrial

Scientific Background

Heat shock 60KD protein (HSP60) is a member of the chaperonin class of protein factors and the nuclear encoded mitochondrial HSP60 is required for the assembly into oligomeric complexes of proteins imported into the mitochondrial matrix. HSP60 is linked head to head comprising approximately 17 kb and consist of 12 exons. HSP60 is a self-molecule, it can downregulate adaptive immune responses by upregulating Tregs innately through TLR2 signaling.